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doi: 10.1155/2016/3286365

This gives the neural tissue a higher susceptibility to peroxidation ( Parkinsons Disease (PD) Pathogenesis: Role of Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation Parkinsons disease is a chronic, progressive neurodegenerative disorder involving the dopaminergic neurons in the substantia nigra pars compacta of the brain (5)

However, not all xenobiotics (including drugs) are conjugated/inactivated by this pathway ( The mercapturic acid pathway ( Figure 1 ) involves the conjugation of the tripeptide, GSH, to xenobiotics (including drugs) to render them more hydrophilic and facilitate their elimination

Understanding the underlying cause is essential to providing effective treatment and restoring normal taste

Apr 122022 Glutathione (GSH) is an antioxidant in plants, animals, fungi, and some bacteria and archaea